Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
序列
该SF3B3 Recombinant Protein的序列请参考该产品的说明书
来源宿主
E.coli
溶解建议
该SF3B3 Recombinant Protein的溶解建议请参考该产品的说明书
保存建议
该SF3B3 Recombinant Protein的保存建议请参考该产品的说明书
其他
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