Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.
序列
该NECTIN3 Recombinant Protein的序列请参考该产品的说明书
来源宿主
E.coli
溶解建议
该NECTIN3 Recombinant Protein的溶解建议请参考该产品的说明书
保存建议
该NECTIN3 Recombinant Protein的保存建议请参考该产品的说明书
其他
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