Metastasis suppressor protein. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. Intracerebroventricular administration induces an increase in serum LH and FSH levels in prepubertal male and female as well as in adult animals.
序列
该KISS1 Recombinant Protein的序列请参考该产品的说明书
来源宿主
E.coli
溶解建议
该KISS1 Recombinant Protein的溶解建议请参考该产品的说明书
保存建议
该KISS1 Recombinant Protein的保存建议请参考该产品的说明书
其他
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