Has an essential role in ciliogenesis, particularly in neuronal and retinal progenitor cells (PubMed:24797473). Phosphorylates KIF3A (PubMed:24797473). Involved in the control of ciliary length (PubMed:24853502). Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (PubMed:24797473, PubMed:24853502). May play a role in cardiac development (By similarity). Regulates intraflagellar transport (IFT) speed and negatively regulates cilium length in a cAMP and mTORC1 signaling -dependent manner and this regulation requires its kinase activity (PubMed:25243405).
序列
该ICK Recombinant Protein的序列请参考该产品的说明书
来源宿主
E.coli
溶解建议
该ICK Recombinant Protein的溶解建议请参考该产品的说明书
保存建议
该ICK Recombinant Protein的保存建议请参考该产品的说明书
其他
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