Nuclear receptor that acts as a key metabolic sensor by regulating the expression of genes involved in bile acid synthesis, cholesterol homeostasis and triglyceride synthesis. Together with the oxysterol receptors NR1H3/LXR-alpha and NR1H2/LXR-beta, acts as an essential transcriptional regulator of lipid metabolism. Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
序列
该NR5A2 Recombinant Protein的序列请参考该产品的说明书
来源宿主
E.coli
溶解建议
该NR5A2 Recombinant Protein的溶解建议请参考该产品的说明书
保存建议
该NR5A2 Recombinant Protein的保存建议请参考该产品的说明书
其他
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