Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia (PubMed:20603001). Together with BBS1, is necessary for correct trafficking of PKD1 to primary cilia (By similarity). Together with the BBSome complex and LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation (PubMed:22072986). May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade (PubMed:20207729). Isoform 2 may be required for proper retinal function and organization (By similarity).
序列
该ARL6 Recombinant Protein (Human)的序列请参考该产品的说明书
来源宿主
该ARL6 Recombinant Protein (Human)的来源宿主请参考该产品的说明书
溶解建议
该ARL6 Recombinant Protein (Human)的溶解建议请参考该产品的说明书
保存建议
该ARL6 Recombinant Protein (Human)的保存建议请参考该产品的说明书
其他
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