SUMO E3 ligase that acts as a regulator of crossing-over during meiosis: required to couple chromosome synapsis to the formation of crossover-specific recombination complexes. Localizes to recombination sites and stabilizes meiosis-specific recombination factors, such as MutS-gamma complex proteins (MSH4 and MSH5) and TEX11. May mediate sumoylation of target proteins MSH4 and/or MSH5, leading to enhance their binding to recombination sites. Acts as a limiting factor for crossover designation and/or reinforcement and plays an antagonist role with CCNB1IP1/HEI10 in the regulation of meiotic recombination (By similarity).
序列
该RNF212 Recombinant Protein (Human)的序列请参考该产品的说明书
来源宿主
该RNF212 Recombinant Protein (Human)的来源宿主请参考该产品的说明书
溶解建议
该RNF212 Recombinant Protein (Human)的溶解建议请参考该产品的说明书
保存建议
该RNF212 Recombinant Protein (Human)的保存建议请参考该产品的说明书
其他
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