Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
序列
该CBX7 Recombinant Protein (Human)的序列请参考该产品的说明书
来源宿主
该CBX7 Recombinant Protein (Human)的来源宿主请参考该产品的说明书
溶解建议
该CBX7 Recombinant Protein (Human)的溶解建议请参考该产品的说明书
保存建议
该CBX7 Recombinant Protein (Human)的保存建议请参考该产品的说明书
其他
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