Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.
序列
该NABP1 Recombinant Protein的序列请参考该产品的说明书
来源宿主
Human
溶解建议
该NABP1 Recombinant Protein的溶解建议请参考该产品的说明书
保存建议
该NABP1 Recombinant Protein的保存建议请参考该产品的说明书
其他
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