Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11063746, PubMed:19478087). It is involved in the negative regulation of the angiotensin-activated signaling pathway (PubMed:28784619). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle (By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein (PubMed:19736320).
序列
该RGS2 Recombinant Protein的序列请参考该产品的说明书
来源宿主
Human
溶解建议
该RGS2 Recombinant Protein的溶解建议请参考该产品的说明书
保存建议
该RGS2 Recombinant Protein的保存建议请参考该产品的说明书
其他
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