The ABC transporters are a large family of conserved proteins that transport a wide variety of molecules across cellular membranes. ABCA1 is a member of the ABC-A sub-family, which acts as a lipid translocator. The molecule was originally identified as a scavenger receptor on macrophages and research shows that ABCA1 also plays a major role in cholesterol metabolism. ABCA1 may play an important role in protecting against cardiovascular disease. Mutations in ABCA1 gene have been associated with Tangier disease, a genetic disorder of lipid metabolism, and the more common Familial HDL deficiency, presenting with many of the same symptoms.
应用类型
Flow cytometry
免疫原
ABCA1 transfected HeLa cells.
来源宿主
Rat
反应性
该Abca1 抗体 - PE Conjugated的反应性请参考该产品的说明书
保存建议
2°C to 8°C
其他
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