- 中文名称
PAK-1,2,3 抗体 (Phospho-Thr402)
- 英文名字
- PAK-1,2,3 Antibody (Phospho-Thr402)
- 供应商
- Aviva Systems Biology
- 产品货号
- aviva-OAPC00214-100UL
- 产品报价
- ¥询价/100ul

- 产品说明书
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- 购买方式
- 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系。本公司所有产品仅供科研使用,不用于临床诊断。
- 产品新闻

- 背景资料
- In mammals, there are several identified isoforms of p21-activated protein kinases or PAKs: alpha -PAK (also known as PAK-1) and beta -PAK (also known as PAK-3) are mostly brain-specific, while gamma -PAK (also known as PAK-2) is expressed ubiquitously (Jakobi et al., 2003). Mutations of the gene coding for PAK-3 are associated with X-linked mental retardation and recent work indicates that PAK-3 is a key regulator of synapse formation and plasticity in the hippocampus (Boda et al., 2004). PAK-3 is thought to play a key role in regulation of cell shape and motility as well as cell death (Jakobi et al., 2003; Walter et al., 1998). Autophosphorylation of Thr402 in the protein has been found to be essential for activation of PAK (Jakobi et al., 2000).
- 应用类型
- WB
- 免疫原
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Thr402 of rat p21 activated kinase 2 (PAK-2). The peptide sequence used is identical in PAK-1, 2 and 3. Note: Thr402 in PAK-2 corresponds to Thr423 in human PAK-1.
- 来源宿主
- Rabbit
- 反应性
- 该PAK-1,2,3 抗体 (Phospho-Thr402)的反应性请参考该产品的说明书
- 保存建议
- Store at -20C; stable for at least one year.
- 其他
- Aviva Systems Biology总部位于加利福尼亚州圣迭戈,在中国北京设有办公室,专注于为研究需求提供多克隆和单克隆抗体、ELISA试剂盒、蛋白质和定制服务。Aviva Systems Biology生产了24,000种经过验证的多克隆抗体,并提供近20,000种ELISA试剂盒,定制实验室服务包括蛋白表达和纯化、抗体开发,以及ELISA的开发、验证和生产。Aviva Systems Biology为与独特物种和靶标相关的研究提供独特工具,研究领域包括转录因子、癌症、心血管、细胞生物学、DNA损伤和修复、表观遗传学、信号转导、细胞分化、干细胞生物学等等。

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