Syntaxins are a family of proteins involved in the docking of synaptic vesicles with the plasma membrane. Syntaxin, along with synaptobrevin and SNAP-25, forms the SNARE complex which mediates synaptic vesicle fusion and exocytosis. Binding of Munc18-1 to the N-terminus of syntaxin 1 has been demonstrated to be essential for exocytic membrane fusion (Khvotchev et al., 2007). Decreased levels of phosphorylated syntaxin 1 in the prefrontal cortex have recently been correlated with schizophrenia (Castillo et al., 2010).
应用类型
WB, IHC
免疫原
Synaptic immunoprecipitate (crude) from human brain.
来源宿主
Mouse
反应性
该Anti-Syntaxin 1A的反应性请参考该产品的说明书
保存建议
Store at -20C; stable for at least one year.
其他
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