Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin-induced tyrosine phosphorylation of paxillin (PXN). May play a critical role as an adapter protein in the formation of the adhesion zone in osteoclasts. Negatively regulates B-cell antigen receptor (BCR) signaling.
应用类型
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
免疫原
Range: Met1 - Ser208
来源宿主
Rabbit
反应性
该LPXN 抗体的反应性请参考该产品的说明书
保存建议
2°C to 8°C|-20°C
其他
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