Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.
Recombinant Human Cyclic nucleotide-gated cation channel alpha-3 protein (1-165AA)
来源宿主
Rabbit
反应性
该CNGA3 抗体的反应性请参考该产品的说明书
保存建议
At -20
其他
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