Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (PubMed:22912744, PubMed:28805828). The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 (PubMed:22912744, PubMed:28805828). TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification (PubMed:22912744, PubMed:28805828).
应用类型
Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
免疫原
Recombinant Human EKC/KEOPS complex subunit TPRKB protein (1-175AA)
来源宿主
Rabbit
反应性
该TPRKB 抗体的反应性请参考该产品的说明书
保存建议
At -20
其他
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