Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Plasma membrane SMS2 can also convert phosphatidylethanolamine (PE) to ceramide phosphatidylethanolamine (CPE). Major form in liver. Required for cell growth in certain cell types. Regulator of cell surface levels of ceramide, an important mediator of signal transduction and apoptosis. Regulation of sphingomyelin (SM) levels at the cell surface affects insulin sensitivity.
应用类型
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Western blot
免疫原
Recombinant Human Phosphatidylcholine:ceramide cholinephosphotransferase 2 protein (1-79AA)
来源宿主
Rabbit
反应性
该SGMS2 抗体的反应性请参考该产品的说明书
保存建议
At -20
其他
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