This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness.
应用类型
WB
免疫原
Recombinant funsion protein containing a sequence corresponding to amino acids 1-255 of human CRY1 (NP_004066.1).
来源宿主
Rabbit
反应性
该CRY1 抗体的反应性请参考该产品的说明书
保存建议
Store at -20°C. Avoid repeated freeze/thaw cycles.
其他
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