- 中文名称
Anti-Connexin 43 抗体 (Phospho-SER368)
- 英文名字
- Anti-Connexin 43 Antibody (Phospho-SER368)
- 供应商
- Aviva Systems Biology
- 产品货号
- aviva-OAAI00634-100UG
- 产品报价
- ￥询价/100ug
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系。本公司所有产品仅供科研使用，不用于临床诊断。
- 产品新闻
- 背景资料
- Gap junction proteins allow the intercellular communication among adjacent cells by passing throμgh small molecules less than 1kDa. It is very important in regulating embryonic development, excitable cell contraction, tissue homeostasis, and normal cell growth and differentiation. Gap junctions are composed of integral membrane proteins from the connexin gene family.
Approximately 20 members have been cloned and characterized in Humans. During intercellular channel formation, six connexin proteins oligomerize into a hemi-channel or connexon followed by connexon trafficking to the plasma membrane.
The intact channel is formed when one hemi-channel docks with a second in an opposing cell. Once assembled, groups of these intercellular channels (termed gap junctional plaques) mediate the passage of amino acids, second messengers, and other metabolites between the connected cytoplasmic domains. The channels can be gated in response to various stimuli, including changes in voltage, pH, and connexin phosphorylation. Regulation of gap junctional communication could occur by controlling any one of the steps mentioned above. Phosphorylation of members of the connexin family of gap junction proteins has been correlated with gap junction assembly.
- 应用类型
- Enzyme-linked immunosorbent assay|Flow cytometry|Immunohistochemistry|Immunoprecipitation|Western blot
- 免疫原
- A synthetic peptide corresponding to the C-terminal region with a phosphorylated Serine368 of human Connexin 43
- 来源宿主
- Rabbit
- 反应性
- 该Anti-Connexin 43 抗体 (Phospho-SER368)的反应性请参考该产品的说明书
- 保存建议
- The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- 其他
- Aviva Systems Biology总部位于加利福尼亚州圣迭戈，在中国北京设有办公室，专注于为研究需求提供多克隆和单克隆抗体、ELISA试剂盒、蛋白质和定制服务。Aviva Systems Biology生产了24,000种经过验证的多克隆抗体，并提供近20,000种ELISA试剂盒，定制实验室服务包括蛋白表达和纯化、抗体开发，以及ELISA的开发、验证和生产。Aviva Systems Biology为与独特物种和靶标相关的研究提供独特工具，研究领域包括转录因子、癌症、心血管、细胞生物学、DNA损伤和修复、表观遗传学、信号转导、细胞分化、干细胞生物学等等。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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