Amylin is a 37 amino acid peptide co-secreted with insulin from pancreatic islet beta-cells. Amylin shares structural similarities with calcitonin gene-related peptide (CGRP) and calcitonin (CT), including an N-terminal ring structure linked by a disulfide bridge, and an amidated C-terminus. The function of Amylin is to maintain the gluocose homoeostasis, include lowered insulin secretion, raised hepatic glucose output, stimulation of glycogenolysis and inhibition of glycogen synthesis in liver cells and in skeletal muscle. Amylin peptide is predominantly found in the beta cells of the pancreas and to a lesser extent in the gastrointestinal tract and nervous system. This Antibody can be used for staining of amylin in normal and diabetic pancreas and pancreatic carcinoma
应用类型
Enzyme-linked immunosorbent assay|Flow cytometry|Immunohistochemistry|Immunoprecipitation|Western blot
免疫原
A synthetic peptide derived from N-term of human Amylin peptide.
来源宿主
Rabbit
反应性
该Anti-Amylin Peptide Polyclonal 抗体的反应性请参考该产品的说明书
保存建议
The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
其他
Aviva Systems Biology总部位于加利福尼亚州圣迭戈，在中国北京设有办公室，专注于为研究需求提供多克隆和单克隆抗体、ELISA试剂盒、蛋白质和定制服务。Aviva Systems Biology生产了24,000种经过验证的多克隆抗体，并提供近20,000种ELISA试剂盒，定制实验室服务包括蛋白表达和纯化、抗体开发，以及ELISA的开发、验证和生产。Aviva Systems Biology为与独特物种和靶标相关的研究提供独特工具，研究领域包括转录因子、癌症、心血管、细胞生物学、DNA损伤和修复、表观遗传学、信号转导、细胞分化、干细胞生物学等等。
