- 中文名称
Anti-TGF- Beta R1 Polyclonal 抗体
- 英文名字
- Anti-TGF- Beta R1 Polyclonal Antibody
- 供应商
- Aviva Systems Biology
- 产品货号
- aviva-OAAI00094-100UG
- 产品报价
- ￥询价/100ug
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系。本公司所有产品仅供科研使用，不用于临床诊断。
- 产品新闻
- 背景资料
- Transforming growth factor beta isoforms (TGF-beta1, 2, 3) play vital roles in regulating cellular growth and differentiation, and they signal throμgh a highly restricted subset of receptors known as TGF-beta type I receptor (TbetaR-I) and TGF-beta type II receptor(TbetaR-II). TGF-beta's specificity for TbetaR-I has been proposed to arise from its pre-helix extension, a five-residue loop that binds in the cleft between TGF-beta and TbetaR-II. TGF-beta binds with high affinity to the type II receptor, a transmembrane protein with a cytoplasmic serine/threonine kinase domain, which requires both its kinase activity and association with another TGF beta-binding protein, the type I receptor, to signal growth inhibition and early gene responses. Receptors I and II associate as interdependent components of a heteromeric complex: receptor I requires receptor II to bind TGF beta, and receptor II requires receptor I to signal. Mutations in TbetaR-I and TbetaR-II gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS).
- 应用类型
- Enzyme-linked immunosorbent assay|Flow cytometry|Immunohistochemistry|Immunoprecipitation|Western blot
- 免疫原
- A synthetic peptide of human TGFbR1
- 来源宿主
- Rabbit
- 反应性
- 该Anti-TGF- Beta R1 Polyclonal 抗体的反应性请参考该产品的说明书
- 保存建议
- The antibodies are stable for 24 months from date of receipt when stored at -20°C to -70°C. The antibodies can be stored at 2-8°C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- 其他
- Aviva Systems Biology总部位于加利福尼亚州圣迭戈，在中国北京设有办公室，专注于为研究需求提供多克隆和单克隆抗体、ELISA试剂盒、蛋白质和定制服务。Aviva Systems Biology生产了24,000种经过验证的多克隆抗体，并提供近20,000种ELISA试剂盒，定制实验室服务包括蛋白表达和纯化、抗体开发，以及ELISA的开发、验证和生产。Aviva Systems Biology为与独特物种和靶标相关的研究提供独特工具，研究领域包括转录因子、癌症、心血管、细胞生物学、DNA损伤和修复、表观遗传学、信号转导、细胞分化、干细胞生物学等等。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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