Microtubules are cylindrical tubes of 20-25 nm indiameter. They are composed of protofilaments which are in turn composed of alpha- and beta- tubulin polymers. Each microtubule is polarized, at one end alpha-subunits are exposed (-) and at the other beta-subunits are exposed (+) .Microtubules act as a scaffold to determine cell shape, and provide a backbone for cell organelles and vesicles to move on, a process that requires motor proteins. The major microtubule motor proteins are kinesin, which generally moves towards the (+) end of the microtubule, and dynein, which generally moves towards the (-) end. Microtubules also form the spindle fibers for separating chromosomes during mitosis.
应用类型
WB
免疫原
This Aviva monoclonal antibody is produced by immunizing mice with a recombinant polypeptide (Aviva SEAL mAb technology) corresponding to surface multi-epitopes of Beta Tubulin.
来源宿主
Mouse
反应性
该betaTub56D 抗体的反应性请参考该产品的说明书
保存建议
Store the product at -20C. Stable for one year from the date of shipment.
其他
Aviva Systems Biology总部位于加利福尼亚州圣迭戈，在中国北京设有办公室，专注于为研究需求提供多克隆和单克隆抗体、ELISA试剂盒、蛋白质和定制服务。Aviva Systems Biology生产了24,000种经过验证的多克隆抗体，并提供近20,000种ELISA试剂盒，定制实验室服务包括蛋白表达和纯化、抗体开发，以及ELISA的开发、验证和生产。Aviva Systems Biology为与独特物种和靶标相关的研究提供独特工具，研究领域包括转录因子、癌症、心血管、细胞生物学、DNA损伤和修复、表观遗传学、信号转导、细胞分化、干细胞生物学等等。
