Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Displays serine/threonine protein kinase activity. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2.
The antiserum was produced against synthesized peptide derived from human CTRO.
来源宿主
Rabbit
反应性
该CIT 抗体的反应性请参考该产品的说明书
保存建议
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