Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may specifically involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of emryonic stem (ES) cell identity.
The antiserum was produced against synthesized peptide derived from human CNOT2 around the phosphorylation site of Ser101.
来源宿主
Rabbit
反应性
该CNOT2 抗体 (Phospho-Ser101)的反应性请参考该产品的说明书
保存建议
-20°C
其他
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