| rn Description rn | rnHAMA Blocking Reagent for use in immunoassays such as Rapid Tests | rn
|---|---|
| rn Background rn | rnHeterophilic Antibody (HA) interference in double-antibody sandwich reaction models can lead to false positive results due to non specific binding to capture and detection reagents. In particular, non specific binding of Human Anti-Mouse Antibody (HAMA) occurs in approximately 10% of immunodiagnostic assays. Other types of HA include, Heterophilic Antibody Goat Antibody (HAGA), Heterophilic Antibody Sheep Antibody (HASA), and Heterophilic Antibody Rabbit Antibody (HARA). This blocking reagent binds to the interferent HAMAs blocking its reaction with capture antibody or conjugated antibody. | rn
| rn Form & Buffer rn | rn10mM PBS, 50% glycerine pH 7.4. | rn
| rn Storage rn | rnStore at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. | rn
| rn Applications rn | rnImmunoassays, Rapid Test | rn
| rn Usage Recommendations rn | rnUse at 1:8-1:10; Recommended for application to double-antibody sandwich assay to eliminate the interference caused by different HA, HAMA in Rapid Tests | rn
| rn Additional Information rn | rnThis HAMA Blocking reagent is a monoclonal antibody | rn
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