SCYL2 is a component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. According to PubMed:15809293, it is a probable serine/threonine-protein kinase that phosphorylates, in vitro, the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L- lysine. According to PubMed:16914521, it has no detectable kinase activity in vitro. It may regulate clathrin-dependent trafficking between the TGN and/or the endosomal system.
应用类型
WB
免疫原
The immunogen is a synthetic peptide directed towards the C-terminal region of Human SCYL2
来源宿主
Rabbit
反应性
Human
保存建议
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
其他
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