FcR Blocking Reagent for human has high affinity receptor for IgG (Fc RI, CD64) but it is not an anti-CD64, which allows its use with pure antibodies. Cells from patients treated with IFN-gamma or G-CSF or from patients subject to acute inflammation upregulate immunoglobulin Fc receptors (FcR) and are therefore particularly sensitive to this nonspecific Cy-binding effect.
产品描述
FcR Blocking Reagent for human has high affinity receptor for IgG (Fc RI, CD64) but it is not an anti-CD64, which allows its use with pure antibodies. Cells from patients treated with IFN-gamma or G-CSF or from patients subject to acute inflammation upregulate immunoglobulin Fc receptors (FcR) and are therefore particularly sensitive to this nonspecific Cy-binding effect.