- 中文名称
Snail Family Transcriptional Repressor 2 / SLUG (SNAI2) Antibody
- 英文名字
- Snail Family Transcriptional Repressor 2 / SLUG (SNAI2) Antibody
- 供应商
- Abbexa
- 产品货号
- abx117024
- 产品报价
- ￥询价/100ug
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868。
- 产品新闻
- 背景资料
- SNAI2 Antibody is a Rabbit Polyclonal antibody against SNAI2. Slug (SNAI2) is a widely expressed transcriptional repressor and member of the Snail family of zinc finger transcription factorsSimilar to the related Snail protein, Slug binds to the E-cadherin promoter region to repress transcription during developmentThe binding of Slug to integrin promoter sequences represses integrin expression and results in reduced cell adhesionDown regulation of E-cadherin expression occurs during the epithelial-mesenchymal transition during embryonic development, a process also exploited by invasive cancer cellsThe tumor suppressor protein p53 induces Slug expression in γ-irradiated cells; Slug protects damaged cells from apoptosis by repressing p53-induced transcription of the proapoptotic Bcl-2 family protein PumaDeletion mutations in the corresponding Slug gene are associated with the pigmentation disorders Waardenburg Syndrome and Piebaldism, while a genetic duplication resulting in Slug overexpression is associated with a collection of congenital heart defects termed tetralogy of Fallot.
- 应用类型
- ELISA, WB, IHC
- 免疫原
- Snail Family Transcriptional Repressor 2 / SLUG (SNAI2)
- 来源宿主
- 兔
- 反应性
- 人，小鼠，大鼠
- 保存建议
- 建议收到该Snail Family Transcriptional Repressor 2 / SLUG (SNAI2) Antibody产品后，储存温度为-20°C。避免重复冻融
- 其他
- Abbexa总部位于英国剑桥的剑桥科学园,是一家专业的全球抗体供应商和蛋白质供应商,致力于为生命科学、药物开发和生物技术领域的科学家和研究者提供最佳的客户体验和高质量的产品。产品涵盖一抗、二抗、蛋白质、ELISA试剂盒、酶以及其他用于研究的试剂盒和工具。无论您是进行学术研究,药物开发,疾病研究还是其它生物学研究,Abbexa的单克隆抗体,多克隆抗体,蛋白质和生物试剂均旨在促进您的研究。如果很难找到合适的抗体来满足您的需求,Abbexa还提供了定制蛋白质,肽和抗体的生产渠道。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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