- 中文名称
Tumor Necrosis Factor (TNF) Antibody
- 英文名字
- Tumor Necrosis Factor (TNF) Antibody
- 供应商
- Abbexa
- 产品货号
- abx117001
- 产品报价
- ￥询价/100ug
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868。
- 产品新闻
- 背景资料
- TNF Antibody is a Rabbit Polyclonal antibody against TNF. TNF-α, the prototypical member of the TNF protein superfamily, is a homotrimeric type-II membrane proteinMembrane-bound TNF-α is cleaved by the metalloprotease TACE/ADAM17 to geneRate a soluble homotrimerBoth membrane and soluble forms of TNF-α are biologically activeTNF-α is produced by a variety of immune cells including T cells, B cells, NK cells, and macrophagesCellular response to TNF-α is mediated through interaction with receptors TNF-R1 and TNF-R2 and results in activation of pathways that favor both cell survival and apoptosis depending on the cell type and biological contextActivation of kinase pathways (including JNK, Erk (p44/42), p38 MAPK, and NF-κB) promotes the survival of cells, while TNF-α-mediated activation of caspase-8 leads to programmed cell deathTNF-α plays a key regulatory role in inflammation and host defense against bacterial infection, notably Mycobacterium tuberculosisThe role of TNF-α in autoimmunity is underscored by blocking TNF-α action to treat rheumatoid arthritis and Crohn’s diseaseThis protein is involved in Immunology.
- 应用类型
- ELISA, WB, IHC
- 免疫原
- TNF
- 来源宿主
- 兔
- 反应性
- 人，小鼠，大鼠
- 保存建议
- 建议收到该Tumor Necrosis Factor (TNF) Antibody产品后，储存温度为-20°C。避免重复冻融
- 其他
- Abbexa总部位于英国剑桥的剑桥科学园,是一家专业的全球抗体供应商和蛋白质供应商,致力于为生命科学、药物开发和生物技术领域的科学家和研究者提供最佳的客户体验和高质量的产品。产品涵盖一抗、二抗、蛋白质、ELISA试剂盒、酶以及其他用于研究的试剂盒和工具。无论您是进行学术研究,药物开发,疾病研究还是其它生物学研究,Abbexa的单克隆抗体,多克隆抗体,蛋白质和生物试剂均旨在促进您的研究。如果很难找到合适的抗体来满足您的需求,Abbexa还提供了定制蛋白质,肽和抗体的生产渠道。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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