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中文名称

Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Antibody

英文名字
Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Antibody
供应商
Abbexa
产品货号
abx110345
产品报价
¥询价/20ug   ¥询价/50ug   ¥询价/100ug   ¥询价/200ug   ¥询价/1mg
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产品新闻
背景资料
VEGFR2 Antibody is a Rabbit Polyclonal antibody against VEGFR2. Recombinant Human VEGFR2 ProteinTyrosine-Protein Kinase That Acts As A Cell-Surface Receptor For Vegfa, Vegfc And VegfdPlays An Essential Role In The Regulation Of Angiogenesis, Vascular Development, Vascular Permeability, And Embryonic HematopoiesisPromotes ProlifeRation, Survival, MigRation And Differentiation Of Endothelial CellsPromotes Reorganization Of The Actin CytoskeletonIsoforms Lacking A Transmembrane Domain, Such As Isoform 2 And Isoform 3, May Function As Decoy Receptors For Vegfa, Vegfc And/Or VegfdIsoform 2 Plays An Important Role As Negative Regulator Of Vegfa- And Vegfc-Mediated Lymphangiogenesis By Limiting The Amount Of Free Vegfa And/Or Vegfc And Preventing Their Binding To Flt4Modulates Flt1 And Flt4 Signaling By Forming HeterodimersBinding Of Vascular Growth Factors To Isoform 1 Leads To The Activation Of Several Signaling CascadesActivation Of Plcg1 Leads To The Production Of The Cellular Signaling Molecules Diacylglycerol And Inositol 1,4,5-Trisphosphate And The Activation Of Protein Kinase CMediates Activation Of Mapk1/Erk2, Mapk3/Erk1 And The Map Kinase Signaling Pathway, As Well As Of The Akt1 Signaling PathwayMediates Phosphorylation Of Pik3R1, The Regulatory Subunit Of Phosphatidylinositol 3-Kinase, Reorganization Of The Actin Cytoskeleton And Activation Of Ptk2/Fak1Required For Vegfa-Mediated Induction Of Nos2 And Nos3, Leading To The Production Of The Signaling Molecule Nitric Oxide (No) By Endothelial CellsPhosphorylates Plcg1Promotes Phosphorylation Of Fyn, Nck1, Nos3, Pik3R1, Ptk2/Fak1 And Src.
应用类型
ELISA, IHC
免疫原
VEGFR2
来源宿主
反应性
保存建议
建议收到该Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Antibody产品后,储存温度为-20°C。避免重复冻融
其他
Abbexa总部位于英国剑桥的剑桥科学园,是一家专业的全球抗体供应商和蛋白质供应商,致力于为生命科学、药物开发和生物技术领域的科学家和研究者提供最佳的客户体验和高质量的产品。产品涵盖一抗、二抗、蛋白质、ELISA试剂盒、酶以及其他用于研究的试剂盒和工具。无论您是进行学术研究,药物开发,疾病研究还是其它生物学研究,Abbexa的单克隆抗体,多克隆抗体,蛋白质和生物试剂均旨在促进您的研究。如果很难找到合适的抗体来满足您的需求,Abbexa还提供了定制蛋白质,肽和抗体的生产渠道。
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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