- 中文名称
STAM Binding Protein (STAMBP) Antibody
- 英文名字
- STAM Binding Protein (STAMBP) Antibody
- 供应商
- Abbexa
- 产品货号
- abx110227
- 产品报价
- ￥询价/20ug ￥询价/50ug ￥询价/100ug ￥询价/200ug ￥询价/1mg
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868。
- 产品新闻
- 背景资料
- STAM Binding Protein (STAMBP) Antibody is a Rabbit Polyclonal antibody against STAMBP. STAMBP is a zinc metalloprotease that specifically cleaves Lys63-linked polyubiquitin chains but does not cleave Lys48-linked polyubiquitin chains. It plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. It potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. It has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. This protein also binds to the SH3 domain of the signal-transducing adaptor molecule required for induction of MYC and cell growth. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization. STAMBP is involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways.
- 应用类型
- ELISA, WB, IHC
- 免疫原
- STAM Binding Protein (STAMBP)
- 来源宿主
- 兔
- 反应性
- 人
- 保存建议
- 建议收到该STAM Binding Protein (STAMBP) Antibody产品后，储存温度为-20°C。避免重复冻融
- 其他
- Abbexa总部位于英国剑桥的剑桥科学园,是一家专业的全球抗体供应商和蛋白质供应商,致力于为生命科学、药物开发和生物技术领域的科学家和研究者提供最佳的客户体验和高质量的产品。产品涵盖一抗、二抗、蛋白质、ELISA试剂盒、酶以及其他用于研究的试剂盒和工具。无论您是进行学术研究,药物开发,疾病研究还是其它生物学研究,Abbexa的单克隆抗体,多克隆抗体,蛋白质和生物试剂均旨在促进您的研究。如果很难找到合适的抗体来满足您的需求,Abbexa还提供了定制蛋白质,肽和抗体的生产渠道。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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