HMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V (D) J recombination.
应用类型
WB
免疫原
HMGB2
来源宿主
兔
反应性
人
保存建议
建议收到该High Mobility Group Protein B2 (HMGB2) Antibody产品后，储存温度为-20°C。避免重复冻融
