EID2 interacts with EP300 and acts as a repressor of MYOD-dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. It may act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex.
应用类型
WB
免疫原
EID2
来源宿主
兔
反应性
人，小鼠
保存建议
建议收到该EP300-Interacting Inhibitor Of Differentiation 2 (EID2) Antibody产品后，储存温度为-20°C。避免重复冻融
