SLUG is a member of the Snail family of C2H2-type zinc finger transcription factors. This protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in the gene encoding SLUG may be associated with sporadic cases of neural tube defects.
应用类型
WB
免疫原
Snail Family Transcriptional Repressor 2 / SLUG (SNAI2)
来源宿主
兔
反应性
人
保存建议
建议收到该Snail Family Transcriptional Repressor 2 / SLUG (SNAI2) Antibody产品后，储存温度为-20°C。避免重复冻融
