Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.
应用类型
WB
免疫原
KLHL12
来源宿主
兔
反应性
人,小鼠
保存建议
建议收到该Kelch-Like Protein 12 (KLHL12) Antibody产品后,储存温度为-20°C。避免重复冻融