This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.
应用类型
WB
免疫原
PPP1R13B
来源宿主
兔
反应性
人
保存建议
建议收到该Apoptosis-Stimulating of P53 Protein 1 (PPP1R13B) Antibody产品后，储存温度为-20°C。避免重复冻融
