PAIP2 acts as a repressor in the regulation of translation initiation of poly (A) containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly (A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly (A) RNP structure organization.
应用类型
WB
免疫原
PAIP2
来源宿主
兔
反应性
人
保存建议
建议收到该Poly(A) Binding Protein Interacting Protein 2 (PAIP2) Antibody产品后，储存温度为-20°C。避免重复冻融
