This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha (IIb) subunits. These subunits play a crucial role in the integrin alpha (IIb) beta (3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25.
应用类型
WB
免疫原
AUP1
来源宿主
兔
反应性
人
保存建议
建议收到该Ancient Ubiquitous Protein 1 (AUP1) Antibody产品后，储存温度为-20°C。避免重复冻融
