PLEKHF1 may induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.
应用类型
WB
免疫原
PLEKHF1
来源宿主
兔
反应性
人
保存建议
建议收到该Pleckstrin Homology And FYVE Domain Containing 1 (PLEKHF1) Antibody产品后，储存温度为-20°C。避免重复冻融
