TPX2 is a spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.
应用类型
WB
免疫原
TPX2
来源宿主
兔
反应性
人
保存建议
建议收到该Targeting Protein For Xklp2 (TPX2) Antibody产品后，储存温度为-20°C。避免重复冻融
