DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V (D) J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity).
应用类型
WB
免疫原
HMGB1
来源宿主
兔
反应性
人
保存建议
建议收到该High Mobility Group Protein B1 (HMGB1) Antibody产品后,储存温度为-20°C。避免重复冻融