Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs.
应用类型
WB
免疫原
TMC6
来源宿主
兔
反应性
人
保存建议
建议收到该Transmembrane Channel-Like Protein 6 (TMC6) Antibody产品后，储存温度为-20°C。避免重复冻融
