This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers.
应用类型
WB
免疫原
PTF1A
来源宿主
兔
反应性
人
保存建议
建议收到该Pancreas Specific Transcription Factor 1a (PTF1A) Antibody产品后，储存温度为-20°C。避免重复冻融
