The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
应用类型
WB
免疫原
APBA2
来源宿主
兔
反应性
小鼠
保存建议
建议收到该Amyloid-Beta A4 Precursor Protein-Binding Family A Member 2 (APBA2) Antibody产品后，储存温度为-20°C。避免重复冻融
