Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.
应用类型
WB
免疫原
5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-1 (PRKAA1)
来源宿主
小鼠
反应性
人
保存建议
建议收到该5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-1 (PRKAA1) Antibody产品后，储存温度为-20°C。避免重复冻融
