- 中文名称
RPTOR Independent Companion of MTOR Complex 2 (RICTOR) Antibody
- 英文名字
- RPTOR Independent Companion of MTOR Complex 2 (RICTOR) Antibody
- 供应商
- Abbexa
- 产品货号
- abx015977
- 产品报价
- ¥询价/100ul

- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻

- 背景资料
- Cell growth is a fundamental biological process whereby cells accumulate mass and increase in size.The mammalian TOR (mTOR) pathway regulates growth by coordinating energy and nutrient signals with growth factor-derived signals.mTOR is a large protein kinase with two different complexes.One complex contains mTOR, G beta L and raptor, which is a target of rapamycin.The other complex, insensitive to rapamycin, includes mTOR, G beta L, Sin1 and rictor.The mTOR-rictor complex phosphorylates Ser473 of Akt/PKB in vitro.This phosphorylation is essential for full Akt/PKB activation.Furthermore, an siRNA knockdown of rictor inhibits Ser473 phosphorylation in 3T3-L1 adipocytes.This complex has also been shown to phosphorylate the rapamycin-resistant mutants of S6K1, another effector of mTOR.
- 应用类型
- ELISA, WB
- 免疫原
- RICTOR
- 来源宿主
- 小鼠
- 反应性
- 人, 猴子, 小鼠
- 保存建议
- 建议收到该RPTOR Independent Companion of MTOR Complex 2 (RICTOR) Antibody产品后,储存温度为-20°C。避免重复冻融
- 其他
- Abbexa总部位于英国剑桥的剑桥科学园,是一家专业的全球抗体供应商和蛋白质供应商,致力于为生命科学、药物开发和生物技术领域的科学家和研究者提供最佳的客户体验和高质量的产品。产品涵盖一抗、二抗、蛋白质、ELISA试剂盒、酶以及其他用于研究的试剂盒和工具。无论您是进行学术研究,药物开发,疾病研究还是其它生物学研究,Abbexa的单克隆抗体,多克隆抗体,蛋白质和生物试剂均旨在促进您的研究。如果很难找到合适的抗体来满足您的需求,Abbexa还提供了定制蛋白质,肽和抗体的生产渠道。

- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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