- 中文名称
Cyclin-Dependent Kinase 1 (CDK1) Antibody
- 英文名字
- Cyclin-Dependent Kinase 1 (CDK1) Antibody
- 供应商
- Abbexa
- 产品货号
- abx015728
- 产品报价
- ￥询价/100ul
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868。
- 产品新闻
- 背景资料
- The cell division control protein cdc2, also known as cyclin-dependent kinase 1 (Cdk1) or p34/cdk1, plays a key role in the control of the eukaryotic cell cycle, where it is required for entry into S-phase and mitosis.Cdc2 exists as a complex with both cyclin A and cyclin B.The best characterized of these associations is the Cdc2 p34 cyclin B complex, which is required for the G2 to M phase transition.Activation of Cdc2 is controlled at several steps including cyclin binding and phosphorylation of threonine 161.However, the critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of Tyr15 and Tyr14.Phosphorylation at Tyr15 and inhibition of Cdc2 is carried out by WEE1 and MIK protein kinases while Tyr15 dephosphorylation and activation of Cdc2 is carried out by the cdc25 phosphatase.The isoform CDC2deltaT is found in breast cancer tissues.Furthermore, cdc2/Cdk1 is a key mediator of neuronal cell death in brain development and degeneration.
- 应用类型
- ELISA, WB, IF/ICC, FCM
- 免疫原
- CDC2
- 来源宿主
- 小鼠
- 反应性
- 人
- 保存建议
- 建议收到该Cyclin-Dependent Kinase 1 (CDK1) Antibody产品后，储存温度为-20°C。避免重复冻融
- 其他
- Abbexa总部位于英国剑桥的剑桥科学园,是一家专业的全球抗体供应商和蛋白质供应商,致力于为生命科学、药物开发和生物技术领域的科学家和研究者提供最佳的客户体验和高质量的产品。产品涵盖一抗、二抗、蛋白质、ELISA试剂盒、酶以及其他用于研究的试剂盒和工具。无论您是进行学术研究,药物开发,疾病研究还是其它生物学研究,Abbexa的单克隆抗体,多克隆抗体,蛋白质和生物试剂均旨在促进您的研究。如果很难找到合适的抗体来满足您的需求,Abbexa还提供了定制蛋白质,肽和抗体的生产渠道。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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