Phospho-ZAP-70 (Tyr493) Antibody detects endogenous levels of ZAP-70 only when phosphorylated at Tyrosine 493. ZAP70 (human) a tyrosine kinase of the Syk family. Associates with the T-cell antigen receptor zeta-chain after TCR stimulation. Phosphorylated by Src-family kinases following antigen receptor activation. Plays a role in lymphocyte activation.
