Phospho-C-RAF (Ser296) Antibody detects endogenous levels of C-RAF only when phosphorylated at Serine 296. Raf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn
