Phospho-IKK beta (Tyr199) Antibody detects endogenous levels of IKK beta only when phosphorylated at Tyrosine 199. IKK-beta is a kinase of the IKK family. Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Preferentially found as a heterodimer with IKK-alpha but also as an homodimer.
